How do you assess the cost-effectiveness of healthcare interventions for rare diseases?

Sample interview questions: How do you assess the cost-effectiveness of healthcare interventions for rare diseases?

Sample answer:

  • Establish the rarity of the disease. The prevalence or incidence of the disease should be low enough to be considered rare. This can be determined using epidemiological data or expert opinion.

  • Identify the relevant outcomes. The outcomes of interest should be relevant to the patients and/or their families. They should also be measurable and meaningful. Common outcomes for rare diseases include survival, quality of life, and cost.

  • Measure the effectiveness of the intervention. The effectiveness of the intervention should be measured using a rigorous research design, such as a randomized controlled trial or a cohort study. The results of the study should be presented in a clear and concise manner.

  • Estimate the costs of the intervention. The costs of the intervention should include all direct and indirect costs, such as the cost of the drug or device, the cost of hospitalization, and the cost of lost productivity. The costs should be estimated using a standard costing methodology.

  • Calculate the cost-effectiveness ratio. The cost-… Read full answer

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